Network forensics: detection and mitigation of botnet malicious code via darknet

Computer malwares are major threats that always find a way to penetrate the network, posing threats to the confidentiality, integrity and the availability of data. Network-borne malwares penetrate networks by exploiting vulnerabilities in networks and systems. IT administrators in campus wide network continue to look for security control solutions to reduce exposure and magnitude of potential threats. However, with multi-user computers and distributed systems, the campus wide network often becomes a breeding ground for botnets

Elemental hydrochemistry assessment on its variation and quality status in Langat River, Western Peninsular Malaysia.

This paper discusses the hydrochemistry variation and its quality status in Langat River, based on the chemistry of major ions, metal concentrations and suitability for drinking purposes. Water samples were collected from 30 different stations to assess their hydrochemical characteristics. The physico-chemical parameters selected were temperature, electrical conductivity, total dissolved solids (TDS), salinity, dissolved oxygen , pH, redox potential, HCO3, Cl, SO4, NO3, Ca, Na, K, Mg, 27Al, 138Ba, 9Be, 111Cd, 59Co, 63Cu, 52Cr, 57Fe, 55Mn, 60Ni, 208Pb, 80Se and 66Zn to investigate the variation of the constituents in the river water. Most of the parameters comply with the Drinking Water Quality Standard of the World Health Organization and the Malaysian National Standard for Drinking Water Quality by the Malaysia Ministry of Health except for EC, TDS, Cl, HCO3, SO4, Na, Mg, Al, Fe and Se. The results show that the Langat River is unsuitable for drinking purposes directly without treatment

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Behavioral analysis and visualization of Fast-Flux DNS

Today, a growing, sophisticated technique called Fast-Flux Service Networks (FFSN) poses a major problem to Internet security. They are increasingly used in many illegal practices including money mule recruitment sites, distribution of malware downloads, illegal adult content, and other forms of Internet fraud. Essentially, FFSN were first used as a Domain Name Server (DNS) switching mechanism that combine distributed command and control, web-based load balancing, and proxy redirection. However, cyber criminals are applying various techniques to subvert detection, retain uptime of their information infrastructure and maximize their financial gain. Hence, this paper proposed to analyze and visualize the behavior of FFSN in order to facilitate FFSN detection. In this study, we collect, classify and monitor over500 domains and by scrutinizing and visualizing the trained data, we discover the new types of fluxing designated as NSName-Flux(NF). The analysis results of NF exposed that FFSN have become extensively sophisticated and dynamic. This exemplifies that visualization is an alternative and effective data exploration method for understanding the complex behaviors of FFSN

Biomonitoring of Malaysian aquatic environments: A review of status and prospects

Anthropogenic stressors are reported to be the major drivers of aquatic pollution all over the world. Combating aquatic pollution requires adequate monitoring and inventorying mechanisms, and biomonitoring with the help of bioindicator organisms can be regarded as a sensitive tool for the evaluation of the biological and ecological significance of aquatic pollution. Bioaccumulation, biochemical alterations, morphological and behavioural approaches, population and community level approaches, and in vitro toxicity tests of aquatic organisms are all common techniques employed in biomonitoring of aquatic environments. In this review, the body of literature dealing with the pollution via biomonitoring in Malaysian aquatic ecosystems is discussed. It is evident from the study that, in Malaysia, biomonitoring by bioaccumulation received more attention than other biomonitoring techniques. Aquatic ecotoxicological research studies are very limited in east Malaysia (Sabah and Sarawak), when compared to west (Peninsular) Malaysia. The potential applications of biomonitoring and its relevance for the Malaysian aquatic ecosystems are discussed. Recommendations for future improvements in the Malaysian aquatic pollution biomonitoring are also made

The value of open-source clinical science in pandemic response: lessons from ISARIC

International audienc